ALLERGIC REACTIONS TO THE COMPONENTS OF DENTAL MATERIALS AND THE POSSIBILITIES OF THEIR DIAGNOSTICS

Most fixed restorations and removable dentures are made from casting alloys and polymers. Many orthodontic appliances are also fabricated from metallic biomaterials. It has been documented in vitro and in vivo, that restorations release to oral cavity many components due to biodegradation processes. Those products may be distributed systemically and locally and could pay a significant role in the induction of oral or/and systemic immunoinflammatory conditions. The complex nature of most of the reactions requires in vivo and in vitro approach to the diagnostics.