CORRECTION OF METABOLIC DISORDERS IN OBESITY IN ADOLESCENTS

The article presents data on the use of the drug ursodeoxycholic acid in hepatomegaly and fatty hepatosis in 50 obese adolescents. The purpose of the work was to study metabolic disorders in obesity in adolescents and the effectiveness of the use of ursodeoxycholic acid in correcting these changes. The subjects of the study were 50 obese adolescents aged 10 to 18 years. The teenagers were divided into 2 groups of 25 people using random sampling. Children of the main group, in addition to non-drug treatment, received the drug ursodesocholic acid in an age-appropriate dosage. The analysis was carried out according to objective examination, instrumental and laboratory studies. Based on the analysis data, it was found that the condition of the liver in adolescents with obesity is characterized by changes in the form of liver enlargement, the appearance of fatty hepatosis and changes in the lipid profile. After completing the study, it was concluded that there was a significant positive clinical and functional dynamics of the disease in the first group while taking ursodeoxycholic acid. In the second group, there was a lack of dynamics and even some deterioration in clinical and functional indicators. The use of ursodeoxycholic acid drugs in addition to non-drug treatment leads to a significant improvement in clinical symptoms and lipid metabolism in adolescents.