Abstract
Acute destructive pancreatitis is a formidable surgical disease that poses a serious problem due to its geographical distribution; the severe form of which is associated with high morbidity and mortality. At the same time, mortality, depending on the volume of the inflammatory process of the pancreas and the severity of the pathology itself, remains at a level of 20% and above. The purpose of the study was to summarize the literature data on the experience of researchers over the past 10 years devoted to the search for the most effective methods of surgical treatment in combination with drug therapy for acute destructive pancreatitis. Pub med, Medline, publications from journals of the CIS countries and the Republic of Kazakhstan were used. After a comprehensive and standardized assessment, only studies that presented experience in complex treatment of acute destructive pancreatitis, including continuous regional arterial administration of drugs, were taken into account.
Keywords
acute destructive pancreatitis (ADP), pancreatic necrosis, continuous regional arterial infusion (CRAI), protease inhibitor, ulinostatinSuggested citation
References
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