ETIOSTRUCTURE AND ANTIBIOTIC RESISTANCE OF PNEUMOTROPIC PATHOGENS IN VENTILATOR-ASSOCIATED PNEUMONIA IN CHILDREN OF THE FIRST TWO MONTHS

The etiostructure of ventilator-associated pneumonia (VAP) and antibiotic resistance of pneumotropic pathogens in sick children of the first two months of life were studied. Materials and methods of research. The object of the study was 98 children with VAP. The collection of biomaterial from the endotracheal tube was carried out by a protected technique developed by us through a vacuum aspirator, eliminating the risk of contamination. The following nutrient media were used in the microbiological study: 5% blood agar, chocolate agar, yolk-salt agar, Saburo medium, Endo medium. Results: in the etiostructure of ventilator associated pneumonia, gram-negative flora prevails (53.42% vs. 31.96%, p<0.05) in almost equal proportions in both full-term and premature infants (p>0.05). The high resistance of the pneumopathogenic gram-positive microflora to all antibiotics widely used in neonatology was revealed: penicillins, cephalosporins of the 2nd and 3rd generation, macrolides of the 1st generation. Gram-negative pneumophilogenic microflora is resistant to almost all antibiotics used in neonatology practice.