ISSN 1694-8882 / e-ISSN 1694-8890
Vol. 18, No. 1, 2026 / Pages 180-198

Long-term outcomes of Heller myotomy for achalasia: 5-year access comparison

osmonalievbakytbek1982@gmail.com

Received 24.10.2025
Revised 30.01.2026
Accepted 27.02.2026

Abstract

Achalasia cardia (AC) is associated with marked impairment of oesophageal food transit and a substantial reduction in quality of life. Despite the widespread use of Heller myotomy, the effect of the type of surgical access on long-term treatment outcomes remains poorly understood. The purpose was to evaluate and compare the five-year results of the Heller myotomy performed by laparoscopic and open access with the analysis of clinical, functional, radiological, and endoscopic parameters. A combined retrospective and prospective multicentre study was conducted, which included 38 patients with confirmed AC. Surgical procedures were performed using open and laparoscopic approaches with antireflux correction. The assessment of efficacy was based on clinical symptoms, radiographic and endoscopic findings, and changes in the symptom severity score. The follow-up period was up to five years. After surgical treatment, there was a statistically significant improvement in all the parameters under study. The severity of symptoms decreased from 8.8 ± 1.5 to 1.7 ± 0.8, the frequency of dysphagia decreased from 100% to 7.9%, and regurgitation decreased from 83.3% to 5.6%. X-ray examination revealed a decrease in the diameter of the oesophagus from 4.8 ± 0.7 to 3.2 ± 0.5 cm and an almost complete elimination of contrast delay. Endoscopic findings confirmed the restoration of cardia patency and a reduction in inflammatory changes of the mucosa. Laparoscopic access demonstrated a more pronounced recovery of evacuation function and a lower incidence of residual disorders compared with open interventions. The results obtained confirmed the high efficiency of Heller myotomy and substantiated the advantage of laparoscopic access in the treatment of AC. The data can be used to optimise surgical tactics and improve the quality of patient treatment, and serve as a basis for further research with sample expansion and standardisation of evaluation criteria

Keywords

achalasia cardia; laparoscopic access; dysphagia; quality of life; clinical outcomes

Suggested citation

APA Style
Osmonaliev, B., Toktosunov, N., Tashev, A., Konurbaeva, J. & Atakulov, B. (2026). Long-term outcomes of Heller myotomy for achalasia: 5-year access comparison. Eurasian Health Journal, 18(1), 180-198. https://doi.org/10.54890/1694-8882-2026-1-180
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Vancouver Style
Osmonaliev, B., Toktosunov, N., Tashev, A., Konurbaeva, J., Atakulov, B.. Long-term outcomes of Heller myotomy for achalasia: 5-year access comparison. Eurasian Health J. 2026;18(1):180-98. https://doi.org/10.54890/1694-8882-2026-1-180
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References

  1. Patel DA, Naik R, Slaughter JC, Higginbotham T, Silver H, Vaezi MF. Weight loss in achalasia is determined by its phenotype. Dis Esophagus. 2018;31(9):doy046. DOI: 10.1093/dote/doy046
  2. Zaninotto G, Bennett C, Boeckxstaens G, Costantini M, Ferguson MK, Pandolfino JE, et al. The 2018 ISDE achalasia guidelines. Dis Esophagus. 2018;31(9):1–29. DOI: 10.1093/dote/doy071
  3. Campos GM, Vittinghoff E, Rabl C, Takata M, Gadenstätter M, Lin F, et al. Endoscopic and surgical treatments for achalasia: A systematic review and meta-analysis. Ann Surg. 2009;249(1):45–57. DOI: 10.1097/SLA.0b013e31818e43ab.
  4. Moonen A, Annese V, Belmans A, Bredenoord AJ, Bruley des Varannes S, Costantini M, et al. Long-term results of the European achalasia trial: A multicentre randomised controlled trial comparing pneumatic dilation versus laparoscopic Heller myotomy. Gut. 2016;65(5):732–9. DOI: 10.1136/gutjnl-2015-310602
  5. Boeckxstaens GE, Annese V, des Varannes SB, Chaussade S, Costantini M, Cuttitta A, et al. Pneumatic dilation versus laparoscopic Heller’s myotomy for idiopathic achalasia. N Engl J Med. 2011;364(19):1807–16. DOI: 10.1056/NEJMoa1010502
  6. Salvador R, Costantini M, Zaninotto G, Morbin T, Rizzetto C, Zanatta L, et al. The preoperative manometric pattern predicts the outcome of surgical treatment for esophageal achalasia. J Gastrointest Surg. 2010;14(11):1635–45. DOI: 10.1007/s11605-010-1318-4
  7. Eckardt VF. Clinical presentations and complications of achalasia. Gastrointest Endosc Clin N Am. 2001;11(2):281–92. DOI: 10.1016/S1052-5157(01)00003-8
  8. Ware JE Jr, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30(6):473–83.
  9. Salvador R, Savarino E, Pesenti E, Spadotto L, Capovilla G, Cavallin F, et al. The impact of Heller myotomy on integrated relaxation pressure in esophageal achalasia. J Gastrointest Surg. 2016;20(1):125–31. DOI: 10.1007/s11605-015-3006-x
  10. Wu JCY. Pneumatic dilation versus laparoscopic Heller’s myotomy for idiopathic achalasia. J Neurogastroenterol Motil. 2011;17(3):324–6. DOI: 10.5056/jnm.2011.17.3.324
  11. Hulselmans M, Vanuytsel T, Degreef T, Sifrim D, Coosemans W, Lerut T, Tack J, et al. Long-term outcome of pneumatic dilation in the treatment of achalasia. Clin Gastroenterol Hepatol. 2010;8(1):30–5.
  12. Vaezi MF, Pandolfino JE, Vela MF. ACG clinical guidelines: Diagnosis and management of achalasia. Am J Gastroenterol. 2013;108(8):1238–49. DOI: 10.1038/ajg.2013.196
  13. Khashab MA, Vela MF, Thosani N, Agrawal D, Buxbaum JL, Abbas Fehmi SM, et al. ASGE guideline on the management of achalasia. Gastrointest Endosc. 2020;91(2):213–27. DOI: 10.1016/j.gie.2019.04.231
  14. Schlottmann F, Luckett DJ, Fine J, Shaheen NJ, Patti MG. Laparoscopic Heller myotomy versus peroral endoscopic myotomy (POEM) for achalasia: A systematic review and meta-analysis. Ann Surg. 2018;267(3):451–60. DOI: 10.1097/SLA.0000000000002311
  15. World Medical Association. World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects. JAMA. 2013;310(20):2191–4. DOI: 10.1001/jama.2013.281053
  16. Swanström LL. Achalasia: treatment, current status and future advances. Korean J Intern Med. 2019;34(6):1173–80. DOI: 10.3904/kjim.2018.439
  17. Familiari P, Greco S, Volkanovska A, Gigante G, Cali A, Boškoski I, Costamagna G. Achalasia: Current treatment options. Expert Rev Gastroenterol Hepatol. 2015;9(8):1101–14. DOI: 10.1586/17474124.2015.1052407
  18. Abir F, Modlin I, Kidd M, Bell R. Surgical treatment of achalasia: Current status and controversies. Dig Surg. 2004;21(3):165–76. DOI: 10.1159/000079341
  19. Jung HK, Hong SJ, Lee OY, Pandolfino J, Park H, Miwa H, et al. 2019 Seoul Consensus on Esophageal Achalasia Guidelines. J Neurogastroenterol Motil. 2020;26(2):180–203. DOI: 10.5056/jnm20014
  20. Gupta V, Hatimi H, Kumar S, Chandra A. Laparoscopic Heller’s myotomy for achalasia cardia: One-time treatment in developing countries? Indian J Surg. 2017;79(5):401–5. DOI: 10.1007/s12262-016-1496-8
  21. Kim SH, Chang Y, Sung SW, Kim J, Kim YT. Video-assisted thoracoscopic surgery for esophageal achalasia: Results of a multicenter study. Surg Laparosc Endosc Percutan Tech. 2016;26(6):e129–34. DOI: 10.1097/SLE.0000000000000402