Том 17, № 4, 2025 / Барактар 168-185

Карылык мезгилиндеги саркопения: эпидемиология, патофизиология жана алдын алуу жана дарылоонун жаңы ыкмалары (адабияттарга сереп)

Кабыл алынган убакыт 15.09.2025
Түзөтүлгөн 04.12.2025
Кабыл алынган 25.12.2025

Аннотация

Саркопения – бул скелет булчуң массасынын прогрессивдүү жоголушу жана булчуң функциясынын начарлашы менен мүнөздөлгөн гериатриялык оору. Бул өсүп жаткан, көп учурда диагноз коюлбай калган ден соолук көйгөйү. Анын улгайган калк арасында таралышы өтө ар түрдүү, жынысына, жашына, негизги ооруларына жана диагностикалык критерийлерине жараша 5 % дан 50 % га чейин. Саркопения диагнозу булчуң массасынын төмөндүгү менен айкалышкан булчуң күчүнүн төмөндүгү же физикалык көрсөткүчтөрдүн төмөндүгү менен тастыкталат. Дарылоого же баалоого бирдиктүү мамиле жок, бул саркопения диагнозун ого бетер татаалдаштырат. Саркопенияны дарылоо жолдоруна фармакологиялык эмес жана фармакологиялык ыкмалар кирет. Фармакологиялык эмес ыкмаларга күч машыгуулары жана жетиштүү тамактануу кирет. Бул эки ыкманын ичинен күч машыгуулары саркопенияны дарылоонун стандарттуу фармакологиялык эмес ыкмасы болуп саналат жана олуттуу оң натыйжалар менен колдоого алынат. Белокту жетиштүү өлчөмдө кабыл алуу, D витамини, антиоксиданттар жана узун чынжырлуу поликаныкпаган май кислоталары сыяктуу айрым диеталык ыкмалар да саркопенияга каршы күрөшүүдө оң таасирин көрсөттү. Учурда АКШнын Азыктүлүк жана дары-дармек башкармалыгы (FDA) саркопенияны дарылоо үчүн эч кандай атайын дарыдармектерди беките элек. Келечектеги изилдөөлөр саркопениянын биологиялык механизмдерине жана диагностикалык ыкмаларды өркүндөтүүгө, мисалы, эрте аныктоо үчүн биомаркерлерге, туруктуу натыйжалуу дарылоо ыкмаларын иштеп чыгууга жана дарылоонун натыйжасын алдын ала айтуу үчүн сезгич индикаторлорду түзүүгө багытталышы керек

Негизги сөздөр

саркопения; аныктамасы; диагнозу; дарылоо; алдын алуу

Цитаталоо

APA Style
Sherieva, N., Garipov, M., Kaipova, S., Arstanbekova, M., Smailova, D. & Mamatov, S. (2025). Sarcopenia in aging: Epidemiology, pathophysiology, and new approaches to prevention and treatment (literature review). Eurasian Health Journal, 17(4), 168-185. https://doi.org/10.54890/1694-8882-2025-4-168
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Vancouver Style
Sherieva, N., Garipov, M., Kaipova, S., Arstanbekova, M., Smailova, D., Mamatov, S.. Sarcopenia in aging: Epidemiology, pathophysiology, and new approaches to prevention and treatment (literature review). Eurasian Health J. 2025;17(4):168-85. https://doi.org/10.54890/1694-8882-2025-4-168
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